Paper of the Month - Archive

June 2017: in a synthetic tour de force featuring consecutive Wittig reactions and a final Nickel-mediated six-fold C-C coupling, Itami and coworkers achieved the first synthesis of a carbon nanobelt.

May 2017: Cristiano Zonta an coworkers describe a metallosupramolecular/dynamic covalent cage whose rate of hydrolytic disassembly can be controlled by the size of ditopic guests.

April 2017: Watson-Crick base pairing with dye-functionalized DNA single strands and an associated colour change of 3D DNA crystals was demonstrated by Seeman and coworkers.

March 2017: Fletcher and colleagues were able to use ultrasensitive optical microscopy for  visualizing the emergence of a complex, autocatalytic system.

February 2017: Walther and coworkers realized social self-sorting of microgel systems by merging colloidal self-assembly with supramolecular interactions.

January 2017: Anderson and coworkers demonstrate paratropic and diatropic ring currents at an unprecedented scale: one of their six-porphyrin nanorings is globally antiaromatic in its four-fold oxidized state (80 π-electrons) and globally aromatic in its six-fould oxidized state (78 π-electrons).

December 2016: Storch and Trapp designed a Rhodium-phosphoramidite catalyst whose non-covalent interaction with a chiral reaction product leads to enantioselective self-amplification.

November 2016: a negative feedback loop was demonstrated by Aprahamian and coworkers in one of their metal-responsive hydrazone switches: above 20 mol% Zn2+, coordination-coupled deprotonation triggers a secondary chemical process that sequesters any Zn2+ above 20 mol%.

October 2016: Goldup and coworkers developed a simple and high-yielding strategy for the iterative synthesis of oligo[n]rotaxanes.

September 2016: The Whitesides group designed a minimalistic, yet ingenious oscillatory network based on disulfides and thioesters. Systems chemistry!

August 2016: Fujita and coworkers report the self-assembly of a gigantic (diameter 8 nm) Pd30L60 icosidodecahedron

July 2016: Berryman and coworkers report an elegant triple helicate that encapsulates iodide via halogen bonding.

June 2016: Leigh and coworkers describe an autonomous rotary motor: a unique out-of-equlibrium system that converts a chemical fuel into persistent rotary motion.

May 2016: Biedermann and Schneider published a comprehensive review article on experimental (non-covalent) binding energies.

April 2016: a distinct water dimer inside a molecular American football: in a synthetic tour de force, Murata and coworkers prepared compound (H2O)2@C70, providing insights on hydrogen bonding in this unusual environment.

March 2016: Otto and coworkers are pushing the boundaries of dynamic covalent systems chemistry: they report the emergence of two sets of self-replicating chemical quasi-species in a complex library made up of two different dithiol building blocks.

February 2016: Stupp and coworkers describe an intriguing case of a simultaneous dynamic covalent AND supramolecular polymerization.

January 2016: You and coworkers established quantitative reactivity scales for reversible reactions, which can be used for predicting equilibrium distributions based on empirical parameters (in analogy to Mayr's reactivity scales for predicting the kinetics of irreversible reactions).

December 2015: the groups of Rojo, Delgado, Nierengarten and Martin have prepared huge fullerene/carbohydrate dendrons that were found to inhibit the infection by an artificial Ebola virus.

November 2015: Zeng and coworkers describe a comprehensive study (combinatorial synthesis, DFT, X-ray, ICP-MS, titrations) on the metal-binding affinities of their tunable pentameric macrocycles.

October 2015: A very elegant dynamic covalent approach for the synthesis of asymmetric hydrophopobic/hydrophilic membranes was reported by Zhang and Barboiu.

September 2015: Gladysz and coworkes describe a new ligand backbone for asymmetric catalysis: certain Michael additions are catalyzed via hydrogen bonding at the periphery of enantiopure Werner complexes comprising a Co(III) centre and three chiral diamine ligands.

August 2015: Chiu and coworkers make use of sodium-templation for the synthesis of interesting oligomeric [2]catenanes

July 2015: In their excellent perspective "Rise of the Molecular Machines", Euan Kay and Dave Leigh tell us "what to make and why." Interestingly, a feature named "March of the Machines" and a comprehensive review on "Artificial Molecular Machines" appeared just a few weeks later.

June 2015: Aida and coworkers report the first case of a supramolecular polymer that forms via a "living" chain-growth process.

May 2015: Giuseppone and coworkers report on a polymeric material that incorporates light-driven rotary motors, which drastically "wind up" the polymer chains, resulting in macroscopic shrinkage of the material. Another fine example of molecular motors performing macroscopic work!

April 2015: Stoddart and coworkers describe a [4]rotaxane that allows stimuli-induced modulation of its solid-state (!) fluorescence.

March 2015: Ivan Huc and coworkers demonstrate surprisingly selective binding of tricky guest fructose in the cavity of helical oligoamide foldamers.

February 2015: George Whitesides has published a thought-inspiring essay on "Reinventing chemistry", including 52 instances of the term system(s) and 25 instances of the term complex(ity).

January 2015: A highly promising non-fullerene electron acceptor for organic solar cells (PCE 4.1% with P3HT) is described by a collaborative research project based at Imperial College, UK.

December 2014: Itami and coworkers describe the first synthesis of CPTs (CycloPhenyleneThienylenes), in which radial conjugation leads to highly unusual electronic properties.

November 2014: Schalley and Jiang review recent progress on integrative self-sorting (a supramolecular "synthesis strategy" also championed by the groups of Schmittel and Nitschke).

October 2014: the groups of Samori and Lehn have studied a dynamic covalent exchange reaction at the solid/liquid interface using scanning tunneling microscopy. 

September 2014: Paul Beer and coworkers have described an interesting [2]rotaxane in which addition of iodide leads to net shuttling away from a hydrogen bonding site towards a halogen bonding site on the thread.

August 2014: From a total of 30 subcomponents, Kay Severin and coworkers have (self-)assembled the largest non-DNA Solomon link to date.

July 2014: The groups of Andrew Cooper and Rahul Banerjee describe two creative approaches for stabilizing porous imine cages and frameworks. 

June 2014: Jeremy Sanders and coworkers have perfected their 'semi-serendipitous' approach for the dynamic covalent synthesis of knots and links.

May 2014: The groups of Pittelkow and Xu independently describe diselenide exchange as a new entry to the toolbox of Dynamic Covalent Chemistry.

April 2014: In a system composed of three different self-assembled M4L4-cages and three different molecular guests, Jonathan Nitscke and coworkers demonstrate impressive control over cage formation (self-sorting), guest encapsulation (selective) and guest release (sequential). 

March 2014: The groups of Ramesh Jasti and Shigeru Yamago report independently on the first synthesis of [5]cycloparaphenylene ([5]CPP).

February 2014: Michael Juricek, J. Fraser Stoddart, Jay S. Siegel et al. report on "Induced-fit catalysis of corannulene bowl-to-bowl inversion".

January 2014: Adam Wilson, Giulio Gasparini and Stefan Matile review "Functional systems with orthogonal dynamic covalent bonds".